Managing Common Accutane Side Effects with Over-the-Counter Relief
- reedspharmacyutah

- Aug 29
- 2 min read
Accutane (isotretinoin) is a prescription medication often used for acne. While it can deliver life-changing results for skin health, many patients experience side effects during treatment. At Reed’s Pharmacy, we understand how important it is to manage these effects safely and effectively. That’s why we’ve highlighted several over-the-counter (OTC) remedies that can bring relief and help you feel more comfortable while on your Accutane journey.
Our pharmacy team is here to guide you through the best options available, so you can focus on healing your skin without unnecessary discomfort.

Navigating Common Side Effects of Accutane
Accutane works by reducing oil production in the skin, which leads to clearer pores and fewer breakouts. However, that same process can also cause dryness, irritation, and sensitivity throughout the body. Knowing how to manage these symptoms with trusted OTC products can make all the difference in your treatment experience. Consult with your provider before taking any OTC medication with Accutane.
OTC Remedies for Dryness and Skin Irritation
Dry or cracked lips: Use a protective lip balm throughout the day. For cracked or bleeding lips, a medicated balm such as Cortibalm may help.
Dry skin: Gentle, fragrance-free moisturizers like Curel or Vanicream Lotion may help restore hydration without irritation.
Rashes or irritation: Hydrocortisone 1% cream alongside moisturizer can reduce itching and redness.
Managing Nasal Dryness and Nosebleeds
Nasal dryness is a frequent complaint among Accutane users. To relieve this:
Try NeilMed Nasogel or a saline nasal spray to keep the nasal passages moist.
Using a humidifier at night can also help reduce nosebleeds linked to dryness.
Supporting Your Body During Treatment
Muscle aches and joint pain: Some patients find relief with L-Carnitine, an OTC supplement that may help ease soreness.
Sun sensitivity: Always apply a broad-spectrum sunscreen like Vanicream Sunscreen before heading outdoors. Accutane makes skin more prone to burns, so sun protection is essential.
Safe Use Tips for OTC Remedies
When using OTC products alongside prescription medications like Accutane, safety is key:
Always follow package instructions and avoid overuse.
Talk with your pharmacist or Physician before starting any supplement or cream, especially if you’re using other medications.
Keep a list of everything you take, including prescription drugs, OTC remedies, and supplements, to help track potential interactions.
Our pharmacists are here to provide personalized recommendations so you can manage Accutane side effects with confidence.
At Reed’s Pharmacy Utah, we’re committed to working with your physician to help you through every step of your treatment. From managing dryness to easing discomfort, our team is here to recommend the right OTC products and answer your questions.



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